Industrial Microbiology

Technology

The final yield of a bioprocess is directly linked to the efficiency of the strain used. Biomillenia’s ultra-high-throughput screening platform, in synergy with digital culturomics, enables the identification and selection of organisms at a speed and scale unmatched by any other platform. While strains for bioprocesses are typically selected from thousands of candidates, we start from millions, which increases the ability to find most productive candidate strains many times over!

These ultra-high throughput capabilities can be used either for the selection of natural strains or as part of a directed evolution process. Special microfluidic chips can be developed to perform the assays. Here is an example of the microfluidic workflow of a yeast-based process:

workflow figure
Figure source: Scientific Reports | 6:27223 | DOI: 10.1038/srep27223

Real case studies

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